Side effects of loperamide (Imodium) include all of the following except?
A. Diarrhea
B. Epigastric pain
C. Dry mouth
D. Anorexia
Correct Answer: A. Diarrhea
Side effects associated with loperamide include CNS fatigue and dizziness, epigastric pain, abdominal cramps, nausea, dry mouth, vomiting, and anorexia. Diarrhea is an indication, not a side effect. Loperamide is a medication used in the treatment of diarrhea. It classifies as an anti-diarrheal agent.
Option B: A number of the adverse events reported during the clinical investigations and post-marketing experience with loperamide are frequent symptoms of the underlying diarrheal syndrome (abdominal pain/discomfort, nausea, vomiting, dry mouth, tiredness, drowsiness, dizziness, constipation, and flatulence).
Option C: Dry mouth has been reported as a side effect of prescription and over-the-counter (OTC) medications, like loperamide, to stop diarrhea. Dry mouth isn’t always just thirst – other symptoms can include difficulty eating, speaking, swallowing, and bad breath, to name but a few.
Option D: Bloating, loss of appetite, stomach pain, and skin rash are also rare side effects of loperamide. Anorexia is found among people who take Imodium, especially for people who are male, 60+ old, and have been taking the drug for < 1 month.
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