Cancer and Oncology Q 85 - Gyan Darpan : Learning Portal
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Saturday, 26 March 2022

Cancer and Oncology Q 85

Specific classification of the chemotherapeutic agent, Vincristine (Oncovin) is:
    A. Hormone modulator
    B. Mitotic inhibitor
    C. Antineoplastic antibiotic
    D. Antimetabolite

Correct Answer: B. Mitotic inhibitor

Option B: Vincristine is a mitotic inhibitor that inhibits mitosis or cell division. Other examples of mitotic inhibitors are paclitaxel, docetaxel, and vinblastine.

Option A: Hormone modulators work by interfering with the activity of hormones. A good example are the selective estrogen receptor modulators (Tamoxifen, Raloxifene, and Ospemifene).
Option C: Antineoplastic antibiotic (e.g., doxorubicin, mitoxantrone, and bleomycin) blocks cell growth by interfering with DNA.
Option D: Antimetabolites (such as Sulfanilamides) work by acting as false metabolites that prevent DNA synthesis.

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