Which of the following associated disorders may the client with Crohn’s disease exhibit?
A. Ankylosing spondylitis
B. Colon cancer
C. Malabsorption
D. Lactase deficiency
Correct Answer: C. Malabsorption
Because of the transmural nature of Crohn’s disease lesions, malabsorption may occur with Crohn’s disease. A number of factors related to Crohn’s disease may contribute to malabsorption, like inflammation. Persistent, long-term inflammation of the small intestine in people with small bowel Crohn’s disease often leads to damage of the intestinal lining. This can interfere with the organ’s ability to absorb nutrients properly.
Option A: Ankylosing spondylitis is more commonly associated with ulcerative colitis. Between 5 and 10% of cases of ankylosing spondylitis (AS) are associated with inflammatory bowel disease (IBD), ulcerative colitis. A much larger percentage of AS patients have subclinical gut inflammation manifested either by endoscopic findings or by histology.
Option B: In general, having ulcerative colitis can increase the risk for colorectal cancer. Recent research shows that colorectal cancer rates are dropping among people with inflammatory bowel diseases such as ulcerative colitis. People with ulcerative colitis should receive regular screenings for colorectal cancer.
Option D: Lactase deficiency is caused by a congenital defect in which an enzyme isn’t present. Lactose intolerance is usually the result of the body not producing enough lactase. Lactase is an enzyme (a protein that causes a chemical reaction to occur) normally produced in the small intestine that’s used to digest lactose. If the client has a lactase deficiency, it means his body does not produce enough lactase.
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