For Jayvin who is taking antacids, which instruction would be included in the teaching plan?
A. "Take the antacids with 8 oz of water."
B. "Avoid taking other medications within 2 hours of this one."
C. "Continue taking antacids even when pain subsides."
D. "Weigh yourself daily when taking this medication."
Correct Answer: B. “Avoid taking other medications within 2 hours of this one.”
Antacids neutralize gastric acid and decrease the absorption of other medications. The client should be instructed to avoid taking other medications within 2 hours of the antacid. The antacids act by neutralizing the acid in the stomach and by inhibiting pepsin, which is a proteolytic enzyme. Each of these cationic salts has a characteristic pharmacological property that determines its clinical use.
Option A: Water, which dilutes the antacid, should not be taken with an antacid. The dose for antacids depends upon the age of the patient, the purpose of administration (neutralization of acid or off-label use), and the presence of other comorbidities like renal or hepatic impairment.
Option C: A histamine receptor antagonist should be taken even when the pain subsides. Calcium salts neutralize gastric acidity resulting in increased gastric and duodenal bulb pH; they additionally inhibit the proteolytic activity of pepsin if the pH is greater than 4 and increase lower esophageal sphincter tone.
Option D: Daily weights are indicated if the client is taking a diuretic, not an antacid. The average therapeutic dose of antacid is 10 to 15 mL (1 tablespoon or one package content) of liquid or 1 to 2 tablets 3 to 4 times a day. Periodic monitoring of calcium and phosphorus plasma concentrations is a suggested practice in patients on chronic therapy.
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