A client is prescribed metaproterenol (Alupent) via a metered-dose inhaler (MDI), two puffs every 4 hours. The nurse instructs the client to report side effects. Which of the following are potential side effects of metaproterenol?
A. Irregular heartbeat
B. Constipation
C. Pedal edema
D. Decreased heart rate.
Correct Answer: A. Irregular heartbeat
Irregular heart rates should be reported promptly to the care provider. Metaproterenol may cause irregular heartbeat, tachycardia, or anginal pain because of its adrenergic effect on the beta-adrenergic receptors in the heart. It is not recommended for use in clients with known cardiac disorders. Metaproterenol does not cause constipation, pedal edema, or bradycardia.
Option B: In children, the most common side effects are diarrhea, nausea, laryngitis, pharyngitis, sinusitis, otitis, and viral infection. The most commonly observed side effects in patients aged 15 years and over were headaches, influenza infection, abdominal pain, cough, and dyspepsia.
Option C: There are some reports of serious adverse events due to angioedema, hypersensitivity, fatigue, confusional state, abnormal dreams, epilepsy, aggression, immune system disorder, hemorrhage, excoriation, eosinophil count increase, pain in extremity, and abdominal pain.
Option D: Tell the doctor right away if any of these unlikely but serious side effects occur: fast/pounding/irregular heartbeat, muscle cramps, weakness.
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