Which of the following is an appropriate nursing intervention for patients who are receiving CNS depressants?
A. Prevent any activity within the hospital setting while on oral muscle relaxants.
B. Make sure that the patient knows that sedation should be minimal with these agents.
C. Cardiovascular stimulation, a common side effect, would lead to hypertension.
D. Make sure the patient’s call light is close by in case of the need for assistance with activities.
Correct Answer: D. Make sure the patient’s call light is close by in case of the need for assistance with activities.
Children and the elderly are more likely to experience paradoxical reactions to benzodiazepines such as tremors, agitation, or visual hallucinations. Elderly or debilitated patients may be more susceptible to the sedative and respiratory depressive effects of lorazepam.
Option A: Patients who receive lorazepam should be cautioned that driving a motor vehicle, operating machinery, or engaging in hazardous or other activities requiring attention and coordination should be delayed for 24 to 48 hours following administration or until the effects of the drug, such as drowsiness, have subsided.
Option B: Patients should be advised that getting out of bed unassisted may result in falling and potential injury if undertaken within 8 hours of receiving lorazepam. Alcoholic beverages should not be consumed for at least 24 to 48 hours after receiving lorazepam injectable due to the additive effects on central nervous system depression seen with benzodiazepines in general.
Option C: The most important risk associated with the intravenous use of lorazepam injection is respiratory depression. Accordingly, airway patency must be assured and respiration monitored closely. Ventilatory support should be given as required.
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