Cancer and Oncology Q 89 - Gyan Darpan : Learning Portal
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Saturday 26 March 2022

Cancer and Oncology Q 89

In which of the following diseases would bone marrow transplantation not be indicated in a newly diagnosed client?
    A. Severe aplastic anemia
    B. Severe combined immunodeficiency
    C. Acute lymphocytic leukemia
    D. Chronic myeloid leukemia

Correct Answer: C. Acute lymphocytic leukemia

Option C: For the first episode of acute lymphocytic leukemia, conventional therapy is superior to bone marrow transplantation. Treatment is usually long-term chemotherapy and is composed of 3 phases (induction, consolidation, and maintenance).

Options A and B: In severe combined immunodeficiency and in severe aplastic anemia, bone marrow transplantation has been employed to replace abnormal stem cells with healthy cells from the donor’s marrow.
Option D: In myeloid leukemia, bone marrow transplantation is done after chemotherapy to infuse healthy marrow and to replace marrow stem cells ablated during chemotherapy.

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