Crohn’s disease can be described as a chronic relapsing disease. Which of the following areas in the GI system may be involved with this disease?
A. The entire length of the large colon.
B. Only the sigmoid area.
C. The entire large colon through the layers of mucosa and submucosa.
D. The small intestine and colon; affecting the entire thickness of the bowel.
Correct Answer: D. The small intestine and colon; affecting the entire thickness of the bowel
Crohn’s disease can involve any segment of the small intestine, the colon, or both, affecting the entire thickness of the bowel. In Crohn’s disease, the inflammation extends through the entire thickness of the bowel wall from the mucosa to the serosa. The disease runs a relapsing and remitting course.
Option A: Ulcerative colitis is an idiopathic inflammatory condition of the colon which results in diffuse friability and superficial erosions on the colonic wall and associated bleeding. It is the most common form of inflammatory bowel disease worldwide.
Option B: Diverticula can form while straining during a bowel movement, such as with constipation. They are most common in the lower portion of the large intestine (called the sigmoid colon). Diverticulosis is very common and occurs in 10% of people over age 40 and in 50% of people over age 60.
Option C: Characteristically, it involves inflammation restricted to the mucosa and submucosa of the colon. Typically, the disease starts in the rectum and extends proximally in a continuous manner. In the United States, the disease accounts for a quarter-million clinician visits annually.
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